Increasing particle therapy biological effectiveness by nuclear reaction-driven binary strategies
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389005%3A_____%2F24%3A00584544" target="_blank" >RIV/61389005:_____/24:00584544 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1201/9781003023920-13" target="_blank" >https://doi.org/10.1201/9781003023920-13</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1201/9781003023920-13" target="_blank" >10.1201/9781003023920-13</a>
Alternative languages
Result language
angličtina
Original language name
Increasing particle therapy biological effectiveness by nuclear reaction-driven binary strategies
Original language description
The ultimate goal of any form of curative radiotherapy resides in achieving local tumor control by suppressing the proliferative ability of all clonogenic cancer cells. If, on the one hand, the dosimetric precision inherent to charged particle therapy, in principle, allows to reduce the risk of adverse effects due to unnecessary dose absorbed by healthy tissues and/or organs at risk, on the other hand cancer radio resistance continues to represent a cause for treatment failure, leading to local recurrence, metastases and poor prognostic outlook. In order to grow and spread, cancer cells develop mutations that allow them to escape recognition and elimination by the host's immune system. Immunotherapy has gained importance in cancer treatment due to its potential to recover the individual patient's immune recognition of cancer and develop an acquired immune response against malignant cells in the entire body.
Czech name
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Czech description
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Classification
Type
C - Chapter in a specialist book
CEP classification
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OECD FORD branch
10304 - Nuclear physics
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
Monte Carlo in Heavy Charged Particle Therapy: New Challenges in Ion Therapy
ISBN
978-03-678-9716-1
Number of pages of the result
24
Pages from-to
191-214
Number of pages of the book
350
Publisher name
CRC Press
Place of publication
Boca Raton
UT code for WoS chapter
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