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Polycationic graft copolymers as carriers for oligonucleotide delivery. Complexes of oligonucleotides with polycationic graft copolymers.

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F01%3A55010258" target="_blank" >RIV/61389013:_____/01:55010258 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Polycationic graft copolymers as carriers for oligonucleotide delivery. Complexes of oligonucleotides with polycationic graft copolymers.

  • Original language description

    Ionic complexes of oligonucleotides and model oligophosphates with high molecular poly(L-lysine) molecules (M w = 134 000) grafted with short poly[N-(2-hydroxypropyl)- methacrylamide] chains (M w = 7000) were studied as systems suitable for gene therapyapplications. Poly(L-lysine) and poly(trimethyl-ammonioethyl methacrylate chloride) homopolycations were used for comparison. PEC parameters were determined by static and dynamic light scattering methods. PECs prepared with an excess of oligophosphates were found to be stable in physiological salt conditions and in the Bovine Serum Albumin solutions.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CD - Macromolecular chemistry

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2001

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Langmuir

  • ISSN

    0743-7463

  • e-ISSN

  • Volume of the periodical

    17

  • Issue of the periodical within the volume

    10

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    7

  • Pages from-to

    3096-3102

  • UT code for WoS article

  • EID of the result in the Scopus database