Cationic graft copolymers as carriers for delivery of antisense-oligonucleotides.

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F03%3A55033092" target="_blank" >RIV/61389013:_____/03:55033092 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Cationic graft copolymers as carriers for delivery of antisense-oligonucleotides.

Original language description

The effect of chemical composition of high-molecular-weight poly(L-lysine) cationic graft copolymers with short poly[N-(2-hydroxypropyl)methacrylamide] grafts on formation and stability of polyelectrolyte complexes with oligonucleotides and model oligomers was tested by light scattering methods as a novel synthetic vector suitable for gene therapy applications. Polyanion exchange reactions were also studied under physiological conditions.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CD - Macromolecular chemistry

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2003

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Macromolecular Bioscience

ISSN

1616-5187

e-ISSN

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Volume of the periodical

3

Issue of the periodical within the volume

8

Country of publishing house

DE - GERMANY

Number of pages

11

Pages from-to

425-435

UT code for WoS article

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EID of the result in the Scopus database

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