Surface modification of hydrogels based on poly(2-hydroxyethyl methacrylate) with extracellular matrix proteins

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F09%3A00082723" target="_blank" >RIV/61389013:_____/09:00082723 - isvavai.cz</a>

Alternative codes found

RIV/68378041:_____/09:00082723 RIV/00064203:_____/09:5431 RIV/00216208:11130/09:5431

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Surface modification of hydrogels based on poly(2-hydroxyethyl methacrylate) with extracellular matrix proteins

Original language description

Infrared attenuated total reflection spectroscopy was used for in situ observation of the deposition of collagen I on poly(2-hydroxyethyl methacrylate-co-methacrylic acid, 2.9%) hydrogels and subsequent attachment of laminin or fibronectin on the collagen surface. The collagen layers with attached laminin or fibronectin were stable on hydrogel surface in physiological solution. The modification with collagen and particularly with collagen and laminin or fibronectin allowed the adhesion and growth of mesenchymal stromal cells and astrocytes on the hydrogel surface.

Czech name

Modifikace povrchu hydrogelů z poly(2-hydroxyethyl methacrylatu) proteiny mezibuněčné hmoty

Czech description

Infračervená reflexní spektroskopie (IR ATR) byla použita pro in situ pozorování depozice kolagenu I na poly(2-hydroxyethyl methacrylate-co-methacrylic acid, 2.9%) hydrogel a následného připojení lamininu nebo fibronektinu na povrch kolagenu. Kolagenovévrstvy s přichyceným lamininem nebo fibronektinem byly stabilní ve fyziologickém roztoku. Modifikace kolagenem a zvláště pak kolagenem s připojeným lamininem nebo fibronektinem umožnila adhezi a růst mesenchymálních stromálních buněk a astrocytů na povrchu hydrogelu.

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CD - Macromolecular chemistry

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2009

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Materials Science-Materials in Medicine

ISSN

0957-4530

e-ISSN

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Volume of the periodical

20

Issue of the periodical within the volume

4

Country of publishing house

GB - UNITED KINGDOM

Number of pages

7

Pages from-to

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UT code for WoS article

000263683900009

EID of the result in the Scopus database

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