Specific cell cultivation on nanofibrous layer

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F10%3A00350418" target="_blank" >RIV/61389013:_____/10:00350418 - isvavai.cz</a>
Alternative codes found
RIV/68378041:_____/10:00350418
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Specific cell cultivation on nanofibrous layer
Original language description
Nanofibrous layers of reproducible thickness and structure (Nanospider technology) were employed as carriers for hepatocytes and their efficiency were evaluated in a laboratory bioreactor. The construction of the functional hepatal bioreactor is particularly given by the positive response of hepatocyte cells to the used carrier layer as well as by the cell morphology, their viability and biological activity in certain period of time. We compared cell growth on collagen with nanofibres electrospun from copolymer (HEMA/EOEMA) and from differently prepared polycaprolactone (PCL) layers. In both cases, the cells showed better morphology or better growth the on controls (collagen). The results obtained in laboratory bioreactor proved the biochemical functionality of the studied system.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CD - Macromolecular chemistry
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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