Synergistic effect of EMF-BEMER-type pulsed weak electromagnetic field and HPMA-bound doxorubicin on mouse EL4 T-cell lymphoma
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F11%3A00370940" target="_blank" >RIV/61389013:_____/11:00370940 - isvavai.cz</a>
Alternative codes found
RIV/61388971:_____/11:00370940
Result on the web
<a href="http://dx.doi.org/10.3109/1061186X.2011.622403" target="_blank" >http://dx.doi.org/10.3109/1061186X.2011.622403</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3109/1061186X.2011.622403" target="_blank" >10.3109/1061186X.2011.622403</a>
Alternative languages
Result language
angličtina
Original language name
Synergistic effect of EMF-BEMER-type pulsed weak electromagnetic field and HPMA-bound doxorubicin on mouse EL4 T-cell lymphoma
Original language description
We have investigated the effects of low-frequency pulsed electromagnetic field (LF-EMF) produced by BEMER device on experimental mouse T-cell lymphoma EL4 growing on conventional and/or athymic (nude) mice. Exposure to EMF-BEMER slowed down the growth oftumor mass and prolonged the survival of experimental animals. The effect was more pronounced in immuno-compromised nude mice compared to conventional ones. Acceleration of tumor growth was never observed. No measurable levels of Hsp 70 or increased levels of specific anti-EL4 antibodies were detected in the serum taken from experimental mice before and at different intervals during the experiment, i.e. before solid tumor appeared, at the time of its aggressive growth, and at the terminal stage of thedisease
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EC - Immunology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/IAA400200702" target="_blank" >IAA400200702: THE EFFECT OF HPMA DRUG BASED THERAPY ON THE LOCAL TUMOR MICROENVIRONMENT</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Drug Targeting
ISSN
1061-186X
e-ISSN
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Volume of the periodical
19
Issue of the periodical within the volume
10
Country of publishing house
GB - UNITED KINGDOM
Number of pages
10
Pages from-to
890-899
UT code for WoS article
000297057100004
EID of the result in the Scopus database
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