The coiled coil motif in polymer drug delivery systems
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F13%3A00388063" target="_blank" >RIV/61389013:_____/13:00388063 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.biotechadv.2012.01.003" target="_blank" >http://dx.doi.org/10.1016/j.biotechadv.2012.01.003</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.biotechadv.2012.01.003" target="_blank" >10.1016/j.biotechadv.2012.01.003</a>
Alternative languages
Result language
angličtina
Original language name
The coiled coil motif in polymer drug delivery systems
Original language description
The coiled coil is a superhelical structural protein motif that has been thoroughly investigated in recent years. Because of the relatively well-understood principles that determine the properties of coiled coil peptides and proteins, macromolecular systems containing the coiled coil motif have been suggested for various applications. This short review focuses on hybrid polymer coiled coil systems designed for drug delivery purposes. After a short introduction, the most important features of the coiledcoils (stability, association number, oligomerization selectivity and orientation of helices) are described, and the factors influencing these characteristics are discussed. Several examples of the most interesting biomedical applications of the polymer-coiled coil systems (according to the authors' opinion) are presented.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CD - Macromolecular chemistry
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Biotechnology Advances
ISSN
0734-9750
e-ISSN
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Volume of the periodical
31
Issue of the periodical within the volume
1
Country of publishing house
GB - UNITED KINGDOM
Number of pages
7
Pages from-to
90-96
UT code for WoS article
000315761200009
EID of the result in the Scopus database
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