Hierarchical antifouling brushes for biosensing applications
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F14%3A00429950" target="_blank" >RIV/61389013:_____/14:00429950 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.snb.2014.06.075" target="_blank" >http://dx.doi.org/10.1016/j.snb.2014.06.075</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.snb.2014.06.075" target="_blank" >10.1016/j.snb.2014.06.075</a>
Alternative languages
Result language
angličtina
Original language name
Hierarchical antifouling brushes for biosensing applications
Original language description
In this report, hierarchically structured diblock copolymer brushes are shown as an effective alternative to limit the increase in fouling caused by the activation of functional groups for the attachment of biorecognition elements. The growth of antifouling diblock copolymer brushes containing hydroxyl- and carboxy-functional top blocks was enabled by the utilization of surface-initiated atom transfer radical polymerization. The fouling from blood plasma is minimized, which is an essential property forthe applications of these surfaces in label-free affinity biosensors for medical diagnostics and other fields that involve complex biological matrices. Furthermore, the increase in fouling associated with the activation of functional groups was significantly lowered. The use of a top block consisting of poly(carboxybetaine acrylamide) displays improved performance relative to a hydroxyl-bearing polymer after activation. A biosensor able to detect a targeted protein spiked in undiluted bl
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CE - Biochemistry
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Sensors and Actuators B - Chemical
ISSN
0925-4005
e-ISSN
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Volume of the periodical
202
Issue of the periodical within the volume
31 October
Country of publishing house
CH - SWITZERLAND
Number of pages
9
Pages from-to
1313-1321
UT code for WoS article
000339994900168
EID of the result in the Scopus database
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