Dendritic high-molecular-weight polymer drug carriers and their conjugates with drugs for treatment of solid tumours
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F15%3A00469013" target="_blank" >RIV/61389013:_____/15:00469013 - isvavai.cz</a>
Alternative codes found
RIV/61388971:_____/15:00469013
Result on the web
<a href="http://www.ic.gc.ca/opic-cipo/cpd/eng/patent/2783393/summary.html?type=number_search&tabs1Index=tabs1_1" target="_blank" >http://www.ic.gc.ca/opic-cipo/cpd/eng/patent/2783393/summary.html?type=number_search&tabs1Index=tabs1_1</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Dendritic high-molecular-weight polymer drug carriers and their conjugates with drugs for treatment of solid tumours
Original language description
The present invention relates to water-soluble high-molecular-weight polymer drug carriers and their conjugates with drugs, derived from dendrimers of the amidoamine and 2,2-bis(hydroxymethyl)propanoic types, the amino and hydroxy end groups of which are attached to semitelechelic copolymers of N-(2 hydroxypropyl)methacrylamide (HPMA) through biodegradable spacers. The polymer carriers and conjugates enable targeted transport notably of anticancer drugs into solid tumors in which biodegradation, the associated controlled drug release and subsequent elimination of polymer carrier from the organism are provided. The polymer carrier conjugated with a cancerostatic for use in targeted therapy of human tumors.
Czech name
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Czech description
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Classification
Type
P - Patent
CEP classification
CD - Macromolecular chemistry
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Patent/design ID
CA2783393
Publisher
CA001 -
Publisher name
Canadian Intellectual Property Office (CIPO)
Place of publication
Gatineau, Québec
Publication country
CA - CANADA
Date of acceptance
Dec 22, 2015
Owner name
Ústav makromolekulární chemie AV ČR, v. v. i. - Mikrobiologický ústav AV ČR, v. v. i.
Method of use
A - Výsledek využívá pouze poskytovatel
Usage type
A - K využití výsledku jiným subjektem je vždy nutné nabytí licence