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Dendritic high-molecular-weight polymer drug carriers and their conjugates with drugs for treatment of solid tumours

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F15%3A00469013" target="_blank" >RIV/61389013:_____/15:00469013 - isvavai.cz</a>

  • Alternative codes found

    RIV/61388971:_____/15:00469013

  • Result on the web

    <a href="http://www.ic.gc.ca/opic-cipo/cpd/eng/patent/2783393/summary.html?type=number_search&tabs1Index=tabs1_1" target="_blank" >http://www.ic.gc.ca/opic-cipo/cpd/eng/patent/2783393/summary.html?type=number_search&tabs1Index=tabs1_1</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Dendritic high-molecular-weight polymer drug carriers and their conjugates with drugs for treatment of solid tumours

  • Original language description

    The present invention relates to water-soluble high-molecular-weight polymer drug carriers and their conjugates with drugs, derived from dendrimers of the amidoamine and 2,2-bis(hydroxymethyl)propanoic types, the amino and hydroxy end groups of which are attached to semitelechelic copolymers of N-(2 hydroxypropyl)methacrylamide (HPMA) through biodegradable spacers. The polymer carriers and conjugates enable targeted transport notably of anticancer drugs into solid tumors in which biodegradation, the associated controlled drug release and subsequent elimination of polymer carrier from the organism are provided. The polymer carrier conjugated with a cancerostatic for use in targeted therapy of human tumors.

  • Czech name

  • Czech description

Classification

  • Type

    P - Patent

  • CEP classification

    CD - Macromolecular chemistry

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Patent/design ID

    CA2783393

  • Publisher

    CA001 -

  • Publisher name

    Canadian Intellectual Property Office (CIPO)

  • Place of publication

    Gatineau, Québec

  • Publication country

    CA - CANADA

  • Date of acceptance

    Dec 22, 2015

  • Owner name

    Ústav makromolekulární chemie AV ČR, v. v. i. - Mikrobiologický ústav AV ČR, v. v. i.

  • Method of use

    A - Výsledek využívá pouze poskytovatel

  • Usage type

    A - K využití výsledku jiným subjektem je vždy nutné nabytí licence