Aggregation behavior of doubly thermoresponsive polysulfobetaine-b-poly(N-isopropylacrylamide) diblock copolymers
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F16%3A00462669" target="_blank" >RIV/61389013:_____/16:00462669 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1021/acs.macromol.6b01186" target="_blank" >http://dx.doi.org/10.1021/acs.macromol.6b01186</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/acs.macromol.6b01186" target="_blank" >10.1021/acs.macromol.6b01186</a>
Alternative languages
Result language
angličtina
Original language name
Aggregation behavior of doubly thermoresponsive polysulfobetaine-b-poly(N-isopropylacrylamide) diblock copolymers
Original language description
A 2-fold thermoresponsive diblock copolymer PSPP430-b-PNIPAM200 consisting of a zwitterionic polysulfobetaine (PSPP) block and a nonionic poly(N-isopropylacrylamide) (PNIPAM) block is prepared by successive RAFT polymerizations. In aqueous solution, the corresponding homopolymers PSPP and PNIPAM feature both upper and lower critical solution temperature (UCST and LCST) behavior, respectively. The diblock copolymer exhibits thermally induced “schizophrenic aggregation behavior in aqueous solutions. Moreover, the ion sensitivity of the cloud point of the zwitterionic PSPP block to both the ionic strength and the nature of the salt offers the possibility to create switchable systems which respond sensitively to changes of the temperature and of the electrolyte type and concentration. The diblock copolymer solutions in D2O are investigated by means of turbidimetry and small-angle neutron scattering (SANS) with respect to the phase behavior and the self-assembled structures in dependence on temperature and electrolyte content. Marked differences of the aggregation below the UCST-type and above the LCST-type transition are observed. The addition of a small amount of NaBr (0.004 M) does not affect the overall behavior, and only the UCST-type transition and aggregate structures are slightly altered, reflecting the well-known ion sensitivity of the zwitterionic PSPP block.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CF - Physical chemistry and theoretical chemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GC15-10527J" target="_blank" >GC15-10527J: Spherical „horse in vacuum“ or applicable micelles? Behavior and shape of nanoparticles – anticancer drug carriers in real blood environment.</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Macromolecules
ISSN
0024-9297
e-ISSN
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Volume of the periodical
49
Issue of the periodical within the volume
17
Country of publishing house
US - UNITED STATES
Number of pages
14
Pages from-to
6655-6668
UT code for WoS article
000383318300053
EID of the result in the Scopus database
2-s2.0-84987623618