Fluorinated 2-alkyl-2-oxazolines of high reactivity: spacer-length-induced acceleration for cationic ring-opening polymerization as a basis for triphilic block copolymer synthesis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F18%3A00483138" target="_blank" >RIV/61389013:_____/18:00483138 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1021/acsmacrolett.7b00954" target="_blank" >http://dx.doi.org/10.1021/acsmacrolett.7b00954</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/acsmacrolett.7b00954" target="_blank" >10.1021/acsmacrolett.7b00954</a>
Alternative languages
Result language
angličtina
Original language name
Fluorinated 2-alkyl-2-oxazolines of high reactivity: spacer-length-induced acceleration for cationic ring-opening polymerization as a basis for triphilic block copolymer synthesis
Original language description
The synthesis of defined triphilic terpolymers with hydrophilic, lyophilic, and fluorophilic blocks is an important challenge as a basis for the development of multicompartment self-assembled structures with potential for, e.g., cascade catalysis and multidrug loading. The synthesis of fluorophilic poly(2-oxazoline)s generally suffers from a very low reactivity of fluorinated 2-oxazoline monomers in cationic ring-opening polymerization (CROP). We report a systematic study on overcoming the extremely low reactivity of 2-perfluoroalkyl-2-oxazolines in CROP by the insertion of methyl and ethyl hydrocarbon spacers between the 2-oxazoline ring and the trifluoromethyl group. The kinetic studies showed the gradual increase of the rate of polymerization with increasing of the hydrocarbon spacer length. The monomer with an ethyl spacer was found to have similar reactivity as 2-alkyl-2-oxazolines and allowed the synthesis of defined triphilic triblock copolymers.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10610 - Biophysics
Result continuities
Project
<a href="/en/project/GA17-00973S" target="_blank" >GA17-00973S: Lipid Cubic Phases for Drug Delivery and Nanocrystallization</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
ACS Macro Letters
ISSN
2161-1653
e-ISSN
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Volume of the periodical
7
Issue of the periodical within the volume
1
Country of publishing house
US - UNITED STATES
Number of pages
4
Pages from-to
7-10
UT code for WoS article
000423016200002
EID of the result in the Scopus database
2-s2.0-85040575229