Embedding of bacterial cellulose nanofibers within PHEMA hydrogel matrices: tunable stiffness composites with potential for biomedical applications

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F18%3A00485031" target="_blank" >RIV/61389013:_____/18:00485031 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1155/2018/5217095" target="_blank" >http://dx.doi.org/10.1155/2018/5217095</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1155/2018/5217095" target="_blank" >10.1155/2018/5217095</a>

Result language
angličtina
Original language name
Embedding of bacterial cellulose nanofibers within PHEMA hydrogel matrices: tunable stiffness composites with potential for biomedical applications
Original language description
Bacterial cellulose (BC) and poly(2-hydroxyethyl methacrylate) (PHEMA) hydrogels are both considered as biocompatible materials with potential use in various biomedical applications including cartilage, cardiovascular stent, and soft tissue engineering. In this work, the “ever-wet” process based on in situ UV radical polymerization of HEMA monomer in BC nanofibrous structure impregnated with HEMA was used, and a series of BC-PHEMA composites was prepared. The composite structures were characterized by ATR FT-IR spectroscopy, WAXD, SEM, and TEM techniques. The strategy of using densified BC material of various cellulose fiber contents was applied to improve mechanical properties. The mechanical properties were tested under tensile, dynamic shear, and relaxation modes. The final composites contained 1 to 20 wt% of BC. The effect of the reinforcement degree on morphology, swelling capacity, and mechanical properties was investigated. The biocompatibility test of BC-PHEMA composites was performed using mouse mesenchymal stem cells.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10404 - Polymer science

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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