Development of novel nanoparticles for MPI
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F20%3A00535233" target="_blank" >RIV/61389013:_____/20:00535233 - isvavai.cz</a>
Alternative codes found
RIV/68378271:_____/20:00535233 RIV/00216208:11110/20:10419944
Result on the web
<a href="https://journal.iwmpi.org/index.php/iwmpi/article/view/303" target="_blank" >https://journal.iwmpi.org/index.php/iwmpi/article/view/303</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.18416/IJMPI.2020.2009019" target="_blank" >10.18416/IJMPI.2020.2009019</a>
Alternative languages
Result language
angličtina
Original language name
Development of novel nanoparticles for MPI
Original language description
A modified procedure for preparation of iron oxide nanoparticles was used to produce nanoparticles suitable for magnetic particle imaging (MPI). Cationic and anionic maghemite particles were prepared and coated by poly(N-(2-hydroxypropyl)methacrylamide)-co-N-[2-(hydroxyamino)-2-oxo-ethyl]-2-methyl-prop-2-enamide. Bare and coated particles were characterized by magnetometry, dynamic light scattering, MR relaxometry, transmission electron microscopy and tested in vitro in a field-free-point MPI scanner. The nanoparticles were compared to Resovist and to differently oxidized particles dedicated for magnetic resonance imaging (control NP). The cores of particles had an average diameter 8.0 nm (cationic ones) and 8.7 nm (anionic ones), hydrodynamic diameter of coated particles in water colloids was 88 nm, and zeta potential +52 mV or –60 mV for cationic or anionic particles respectively). Cationic particles provided at MPI lower signal-to-noise ratio than Resovist, while anionic higher by 25%. Also signal dispersion to surrounding voxel was smaller. The worst results were reached in the case of control NP.
Czech name
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Czech description
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Classification
Type
J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database
CEP classification
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OECD FORD branch
10404 - Polymer science
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
International Journal on Magnetic Particle Imaging
ISSN
2365-9033
e-ISSN
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Volume of the periodical
6
Issue of the periodical within the volume
2 Suppl. 1
Country of publishing house
DE - GERMANY
Number of pages
3
Pages from-to
1-3
UT code for WoS article
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EID of the result in the Scopus database
2-s2.0-85090281088