New self-supporting polymer thin film for nanoparticle analysis in STEM/TEM
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F25%3A00639798" target="_blank" >RIV/61389013:_____/25:00639798 - isvavai.cz</a>
Alternative codes found
RIV/68081731:_____/25:00639798 RIV/00216224:90127/25:00143924
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S2666523925001692" target="_blank" >https://www.sciencedirect.com/science/article/pii/S2666523925001692</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.apsadv.2025.100859" target="_blank" >10.1016/j.apsadv.2025.100859</a>
Alternative languages
Result language
angličtina
Original language name
New self-supporting polymer thin film for nanoparticle analysis in STEM/TEM
Original language description
The demand for high-resolution imaging of nanomaterials continues to grow across disciplines. However, conventional support films for transmission and scanning transmission electron microscopy (TEM/STEM) are often limited by low beam resistance, suboptimal resolution, toxicity concerns, and high production costs. This study introduces a new application of a self-supporting, biocompatible thin film composed of hydrophilic, crosslinked poly[N-(2-hydroxypropyl)methacrylamide] (p(HPMA)) as an alternative to traditional carbon or organic polymer supports. The film forms a stable, continuous interfacial layer that promotes homogeneous nanoparticle dispersion and minimizes aggregation, critical factors for accurate analysis of nanoscale interfacial interactions. By embedding nanoparticles within the hydrated polymer matrix, the film provides a consistent and reproducible interface, enabling detailed observation of particle behavior, stability, and interactions at both solid-liquid and solid-vacuum boundaries. Resolution measurements show improvements of up to 29% over Formvar and 32% over graphene oxide. Film thicknesses range from 3.5 to 22.9 nm, spanning the holes in Lacey and Quantifoil grids. The film is produced using a rapid, scalable casting method using standard laboratory materials. TEM and STEM imaging confirm its structural and beam stability under accelerating voltages up to 200 kV. Nanoparticle dispersion and film integrity are preserved for at least six months. These findings highlight the potential of this polymer-based support film as a cost-effective and sustainable platform for high-resolution electron microscopy, with broad relevance to colloid and interface science, nanomedicine, and environmental nanotechnology.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10404 - Polymer science
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Applied Surface Science Advances
ISSN
2666-5239
e-ISSN
2666-5239
Volume of the periodical
30
Issue of the periodical within the volume
December
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
15
Pages from-to
100859
UT code for WoS article
001578753900001
EID of the result in the Scopus database
2-s2.0-105016804822