Novel iron complexes bearing N6-substituted adenosine derivatives: Synthesis, magnetic, Fe-57 Mossbauer, DFT, and in vitro cytotoxicity studies

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F08%3A00325895" target="_blank" >RIV/61389030:_____/08:00325895 - isvavai.cz</a>

Result on the web

—

DOI - Digital Object Identifier

—

Result language

angličtina

Original language name

Novel iron complexes bearing N6-substituted adenosine derivatives: Synthesis, magnetic, Fe-57 Mossbauer, DFT, and in vitro cytotoxicity studies

Original language description

Iron complexes (1-7) involving N6-benzyladenosine derivatives of the predominant composition [Fe(L-n)Cl-3]center dot H2O {where L-1 = N6-(2-fluorobenzyl)adenosine (1), L-2 = N6-(4-fluorobenzyl)adenosine (2), L-3 = N6-(2-trifluoromethylbenzyl)adenosine (3), L-4 = N6-(3-trifluoromethylbenzyl)adenosine (4), L-5 = N6-(4-trifluoromethylbenzyl)adenosine (5), L-6 = N6-(4-trifluoromethoxybenzyl)adenosine (6), and L-7 = N6-(4-chlorobenzyl)adenosine (7)} have been synthesized. The compounds have been characterized by elemental analysis, variable-temperature and in-field Fe-57 Mossbauer, ES+ MS, FTIR, H-1 and C-13 NMR spectroscopies, magnetochemical and conductivity measurements, thermal (TGA/DSC/DTA) analyses, and DFT calculations. It has been found that the organic molecule is coordinated to iron via N7 atom of the appropriate adenosine derivative and the products are represented by mixtures of complexes with various iron oxidation (Fe-III/Fe-II) and spin states (S = 5/2, 4/2, 3/2, 2/2) and geo

Czech name

Novel iron complexes bearing N6-substituted adenosine derivatives: Synthesis, magnetic, Fe-57 Mossbauer, DFT, and in vitro cytotoxicity studies

Czech description

Novel iron complexes bearing N6-substituted adenosine derivatives: Synthesis, magnetic, Fe-57 Mossbauer, DFT, and in vitro cytotoxicity studies.

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CE - Biochemistry

OECD FORD branch

—

Project

—

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2008

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Bioorganic & Medicinal Chemistry

ISSN

0968-0896

e-ISSN

—

Volume of the periodical

16

Issue of the periodical within the volume

18

Country of publishing house

GB - UNITED KINGDOM

Number of pages

10

Pages from-to

—

UT code for WoS article

000259173400046

EID of the result in the Scopus database

—