Evaluation of Antimicrobial and Anti-Inflammatory Activities of Seed Extracts from Six Nigella Species

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F09%3A00335914" target="_blank" >RIV/61389030:_____/09:00335914 - isvavai.cz</a>

Alternative codes found

RIV/60460709:41210/09:29797 RIV/60460709:41610/09:29797

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Evaluation of Antimicrobial and Anti-Inflammatory Activities of Seed Extracts from Six Nigella Species

Original language description

Seed extracts from six species of the genus Nigella (Family Ranunculaceae)-Nigella arvensis, Nigella damascena, Nigella hispanica, Nigella nigellastrum, Nigella orientalis, and Nigella sativa-obtained by successive extraction with n-hexane, chloroform, and methanol, were tested for their antimicrobial activity against 10 strains of pathogenic bacteria and yeast using the microdilution method as well as for anti-inflammatory properties by in vitro cyclooxygenase (COX)-1 and COX-2 assay. Chemical characterization of active extracts was carried out including free and fixed fatty acid analysis. Comparison of antimicrobial activity showed that N. arvensis chloroform extract was the most potent among all species tested, inhibiting Gram-positive bacterial andyeast strains with minimum inhibitory concentration (MIC) values ranging from 0.25 to 1 mg/mL.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EI - Biotechnology and bionics

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2009

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Medicinal Food

ISSN

1096-620X

e-ISSN

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Volume of the periodical

12

Issue of the periodical within the volume

2

Country of publishing house

US - UNITED STATES

Number of pages

8

Pages from-to

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UT code for WoS article

000266279000023

EID of the result in the Scopus database

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