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Transcriptomic response of Arabidopsis thaliana (L.) Heynh. roots to ibuprofen

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F17%3A00476651" target="_blank" >RIV/61389030:_____/17:00476651 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11310/17:10361544

  • Result on the web

    <a href="http://dx.doi.org/10.1080/15226514.2016.1267697" target="_blank" >http://dx.doi.org/10.1080/15226514.2016.1267697</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1080/15226514.2016.1267697" target="_blank" >10.1080/15226514.2016.1267697</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Transcriptomic response of Arabidopsis thaliana (L.) Heynh. roots to ibuprofen

  • Original language description

    Surface waters in urban areas are contaminated by ibuprofen (IBP), a popular and extensively used anti-inflammatory drug. In this study, we investigated the transcriptomic response in Arabidopsis thaliana (L.) Heynh. roots with the aim of revealing genes that are potentially involved in IBP detoxification and elucidating the effect of IBP on plants. IBP upregulated 63 and downregulated 38 transcripts (p-value < 0.1, fold change ≥2) after 2-day exposure to a 5-µM (1.03 mg/L) concentration of IBP under hydroponic conditions. Although the IBP concentration used in the experiment was highly relative to the concentrations found in rivers and wastewater, the number of genes with transcriptional changes was relatively low. The upregulation of cytochrome P450s, glutathione S-transferases, and UDP-glycosyltransferases indicates the occurrence of IBP oxidation in the first phase, followed by conjugation with glutathione and sugar in the second detoxification phase. ABC transporters could be involved in the transport of IBP and its metabolites. The identification of genes potentially involved in IBP detoxification could be useful in an IBP phytoremediation approach.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10611 - Plant sciences, botany

Result continuities

  • Project

    <a href="/en/project/GA14-22593S" target="_blank" >GA14-22593S: Metabolism of selected non-steroidal anti-inflammatory drugs in plants and its environmental consequences</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2017

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    International Journal of Phytoremediation

  • ISSN

    1522-6514

  • e-ISSN

  • Volume of the periodical

    19

  • Issue of the periodical within the volume

    8

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    6

  • Pages from-to

    695-700

  • UT code for WoS article

    000402041800001

  • EID of the result in the Scopus database

    2-s2.0-85019615193