Transcriptomic Response of Arabidopsis thaliana Exposed to CuO Nanoparticles, Bulk Material, and Ionic Copper
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F17%3A00479928" target="_blank" >RIV/61389030:_____/17:00479928 - isvavai.cz</a>
Alternative codes found
RIV/67985858:_____/17:00479928 RIV/00216208:11310/17:10370366
Result on the web
<a href="http://dx.doi.org/10.1021/acs.est.7b02265" target="_blank" >http://dx.doi.org/10.1021/acs.est.7b02265</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/acs.est.7b02265" target="_blank" >10.1021/acs.est.7b02265</a>
Alternative languages
Result language
angličtina
Original language name
Transcriptomic Response of Arabidopsis thaliana Exposed to CuO Nanoparticles, Bulk Material, and Ionic Copper
Original language description
Engineered nanoparticles (ENPs) exhibit unique properties advantageous in a number of applications, but they also represent potential health and environmental risks. In this study, we investigated the phytotoxic mechanism of CuO ENPs using transcriptomic analysis and compared this response with the response to CuO bulk particles and ionic Cu 2+ . Ionic Cu 2+ at the concentration of 0.16 mg L1 changed transcription of 2692 genes (p value of < 0.001, fold change of ≥2) after 7 days of exposure, whereas CuO ENPs and bulk particles (both in the concentration of 10 mg L1 ) altered the expression of 922 and 482 genes in Arabidopsis thaliana roots, respectively. The similarity between transcription profiles of plants exposed to ENPs and ionic Cu 2+ indicated that the main factor in phytotoxicity was the release of Cu 2+ ions from CuO ENPs after 7 days of exposure. The effect of Cu 2+ ions was evident in all treatments, as indicated by the down-regulation of genes involved in metal homeostasis and transport and the up-regulation of oxidative stress response genes. ENPs were more soluble than bulk particles, resulting in the up-regulation of metallochaperone-like genes or the down-regulation of aquaporins and metal transmembrane transporters that was also characteristic for ionic Cu 2+ exposure.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10611 - Plant sciences, botany
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Environmental Science and Technology
ISSN
0013-936X
e-ISSN
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Volume of the periodical
51
Issue of the periodical within the volume
18
Country of publishing house
US - UNITED STATES
Number of pages
11
Pages from-to
10814-10824
UT code for WoS article
000411549800060
EID of the result in the Scopus database
2-s2.0-85029690803