Evolutionarily distant streptophyta respond differently to genotoxic stress

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F17%3A00485767" target="_blank" >RIV/61389030:_____/17:00485767 - isvavai.cz</a>

Alternative codes found

RIV/68081707:_____/17:00485767 RIV/60077344:_____/17:00485767 RIV/61388971:_____/17:00485767 RIV/00216224:14740/17:00095507

Result on the web

<a href="http://dx.doi.org/10.3390/genes8110331" target="_blank" >http://dx.doi.org/10.3390/genes8110331</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/genes8110331" target="_blank" >10.3390/genes8110331</a>

Result language

angličtina

Original language name

Evolutionarily distant streptophyta respond differently to genotoxic stress

Original language description

Research in algae usually focuses on the description and characterization of morpho—and phenotype as a result of adaptation to a particular habitat and its conditions. To better understand the evolution of lineages we characterized responses of filamentous streptophyte green algae of the genera Klebsormidium and Zygnema, and of a land plant—the moss Physcomitrella patens—to genotoxic stress that might be relevant to their environment. We studied the induction and repair of DNA double strand breaks (DSBs) elicited by the radiomimetic drug bleomycin, DNA single strand breaks (SSB) as consequence of base modification by the alkylation agent methyl methanesulfonate (MMS) and of ultra violet (UV)-induced photo-dimers, because the mode of action of these three genotoxic agents is well understood. We show that the Klebsormidium and Physcomitrella are similarly sensitive to introduced DNA lesions and have similar rates of DSBs repair. In contrast, less DNA damage and higher repair rate of DSBs was detected in Zygnema, suggesting different mechanisms of maintaining genome integrity in response to genotoxic stress. Nevertheless, contrary to fewer detected lesions is Zygnema more sensitive to genotoxic treatment than Klebsormidium and Physcomitrella.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10611 - Plant sciences, botany

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Genes

ISSN

2073-4425

e-ISSN

—

Volume of the periodical

8

Issue of the periodical within the volume

11

Country of publishing house

CH - SWITZERLAND

Number of pages

13

Pages from-to

—

UT code for WoS article

000416800600041

EID of the result in the Scopus database

2-s2.0-85034731691