Plant Hormone Cytokinins for Modulating Human Aging and Age-Related Diseases

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F17%3A00507476" target="_blank" >RIV/61389030:_____/17:00507476 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1007/978-3-319-63001-4_14" target="_blank" >http://dx.doi.org/10.1007/978-3-319-63001-4_14</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/978-3-319-63001-4_14" target="_blank" >10.1007/978-3-319-63001-4_14</a>

Result language
angličtina
Original language name
Plant Hormone Cytokinins for Modulating Human Aging and Age-Related Diseases
Original language description
Cytokinins are phytohormones that regulate plant growth, development and senescence. Experiments both in vitro and in vivo demonstrate that they can also have diverse effects on animal cells and tissues. Particularly interesting is their ability to protect cells against various forms of stress and prevent some detrimental effects of cell aging. For example, human skin fibroblasts cultured in the presence of kinetin or trans-zeatin retain some characteristics of cells of lower passage. Kinetin is even able to increase the lifespan of invertebrates. In this chapter, we review protective effects of cytokinins in animals at molecular, cellular, tissue and organismal levels. We also discuss potential application of cytokinins for the treatment of age-related diseases, including neurodegenerations, inflammatory diseases and disorders caused by aberrant cell proliferation.
Czech name
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Czech description
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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