Plant Hormone Cytokinins for Modulating Human Aging and Age-Related Diseases
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F17%3A73584929" target="_blank" >RIV/61989592:15310/17:73584929 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1007/978-3-319-63001-4_14" target="_blank" >http://dx.doi.org/10.1007/978-3-319-63001-4_14</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/978-3-319-63001-4_14" target="_blank" >10.1007/978-3-319-63001-4_14</a>
Alternative languages
Result language
angličtina
Original language name
Plant Hormone Cytokinins for Modulating Human Aging and Age-Related Diseases
Original language description
Cytokinins are phytohormones that regulate plant growth, development and senescence. Experiments both in vitro and in vivo demonstrate that they can also have diverse effects on animal cells and tissues. Particularly interesting is their ability to protect cells against various forms of stress and prevent some detrimental effects of cell aging. For example, human skin fibroblasts cultured in the presence of kinetin or trans-zeatin retain some characteristics of cells of lower passage. Kinetin is even able to increase the lifespan of invertebrates. In this chapter, we review protective effects of cytokinins in animals at molecular, cellular, tissue and organismal levels. We also discuss potential application of cytokinins for the treatment of age-related diseases, including neurodegenerations, inflammatory diseases and disorders caused by aberrant cell proliferation.
Czech name
—
Czech description
—
Classification
Type
C - Chapter in a specialist book
CEP classification
—
OECD FORD branch
30104 - Pharmacology and pharmacy
Result continuities
Project
<a href="/en/project/LO1204" target="_blank" >LO1204: Sustainable development of research in the Centre of the Region Haná</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
Hormones in Ageing and Longevity
ISBN
978-3-319-63000-7
Number of pages of the result
25
Pages from-to
311-335
Number of pages of the book
335
Publisher name
Springer
Place of publication
Heidelberg
UT code for WoS chapter
—