Phenolic and flavonoid production and antimicrobial activity of Gymnosporia buxifolia (L.) Szyszyl cell cultures

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F18%3A00497003" target="_blank" >RIV/61389030:_____/18:00497003 - isvavai.cz</a>

Alternative codes found

RIV/61989592:15310/18:73591893

Result on the web

<a href="http://dx.doi.org/10.1007/s10725-018-0432-2" target="_blank" >http://dx.doi.org/10.1007/s10725-018-0432-2</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s10725-018-0432-2" target="_blank" >10.1007/s10725-018-0432-2</a>

Result language

angličtina

Original language name

Phenolic and flavonoid production and antimicrobial activity of Gymnosporia buxifolia (L.) Szyszyl cell cultures

Original language description

Gymnosporia buxifolia (Celastraceae) is a well-known traditional medicinal plant used to treat various diseases. The aim of the study was to quantify the total phenolic and flavonoid content of cell biomass of G. buxifolia developed in vitro using plant growth regulators (PGRs), phloroglucinol (PG) and an antagonist of cytokinin activity 6-(2-hydroxy-3-methylbenzylamino) purine (PI55). The antibacterial activity of calli was also evaluated. The accumulation of phenolic contents and its antibacterial activity in the cell biomass varied between the treatments as well as the mother plant. Generally, a higher accumulation of phenolic contents translated to improved activity against selected pathogenic bacteria. This was apparent in biomass derived from solid and liquid MS media containing combinations of 5 µM PG, 1.5 µM benzyladenine (BA) or meta-topolin (mT) with or without 1 µM picloram (Pic) and 5 µM PG or PI55, 1 µM BA with or without 0.5 µM Pic respectively. The choice of PGRs, PG and PI55 treatments used during in vitro cell culture systems influenced the therapeutic potential of G. buxifolia. Our results indicate that the cell biomass from suspension and/or solid culture of G. buxifolia could be promising as antibacterial agents with possible applications in the pharmaceutical industry.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10611 - Plant sciences, botany

Project

<a href="/en/project/LO1204" target="_blank" >LO1204: Sustainable development of research in the Centre of the Region Haná</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Plant Growth Regulation

ISSN

0167-6903

e-ISSN

—

Volume of the periodical

86

Issue of the periodical within the volume

3

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

6

Pages from-to

333-338

UT code for WoS article

000449811000001

EID of the result in the Scopus database

2-s2.0-85052616309