Root Adaptation to H 2 O 2Induced Oxidative Stress by ARF-GEF BEN1- and Cytoskeleton-Mediated PIN2 Trafficking
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F19%3A00503033" target="_blank" >RIV/61389030:_____/19:00503033 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14740/19:00108185
Result on the web
<a href="http://dx.doi.org/10.1093/pcp/pcz001" target="_blank" >http://dx.doi.org/10.1093/pcp/pcz001</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1093/pcp/pcz001" target="_blank" >10.1093/pcp/pcz001</a>
Alternative languages
Result language
angličtina
Original language name
Root Adaptation to H 2 O 2Induced Oxidative Stress by ARF-GEF BEN1- and Cytoskeleton-Mediated PIN2 Trafficking
Original language description
Abiotic stress poses constant challenges for plant survival and is a serious problem for global agricultural productivity. On a molecular level, stress conditions result in elevation of reactive oxygen species (ROS) production causing oxidative stress associated with oxidation of proteins and nucleic acids as well as impairment of membrane functions. Adaptation of root growth to ROS accumulation is facilitated through modification of auxin and cytokinin hormone homeostasis. Here, we report that in Arabidopsis root meristem, ROS-induced changes of auxin levels correspond to decreased abundance of PIN auxin efflux carriers at the plasma membrane (PM). Specifically, increase in H 2 O 2 levels affects PIN2 endocytic recycling. We show that the PIN2 intracellular trafficking during adaptation to oxidative stress requires the function of the ADP-ribosylation factor (ARF)-guanine-nucleotide exchange factor (GEF) BEN1, an actin-associated regulator of the trafficking from the PM to early endosomes and, presumably, indirectly, trafficking to the vacuoles. We propose that H 2 O 2 levels affect the actin dynamics thus modulating ARF-GEF-dependent trafficking of PIN2. This mechanism provides a way how root growth acclimates to stress and adapts to a changing environment.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10608 - Biochemistry and molecular biology
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Plant and Cell Physiology
ISSN
0032-0781
e-ISSN
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Volume of the periodical
60
Issue of the periodical within the volume
2
Country of publishing house
JP - JAPAN
Number of pages
19
Pages from-to
255-273
UT code for WoS article
000459634300002
EID of the result in the Scopus database
2-s2.0-85062505498