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Mitotic chromosome organization: General rules meet species-specific variability

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F20%3A00531604" target="_blank" >RIV/61389030:_____/20:00531604 - isvavai.cz</a>

  • Result on the web

    <a href="http://doi.org/10.1016/j.csbj.2020.01.006" target="_blank" >http://doi.org/10.1016/j.csbj.2020.01.006</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.csbj.2020.01.006" target="_blank" >10.1016/j.csbj.2020.01.006</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Mitotic chromosome organization: General rules meet species-specific variability

  • Original language description

    Research on the formation of mitotic chromosomes from interphase chromatin domains, ongoing for several decades, made significant progress in recent years. It was stimulated by the development of advanced microscopic techniques and implementation of chromatin conformation capture methods that provide new insights into chromosome ultrastructure. This review aims to summarize and compare several models of chromatin fiber folding to form mitotic chromosomes and discusses them in the light of the novel findings. Functional genomics studies in several organisms confirmed condensins and cohesins as the major players in chromosome condensation. Here we compare available data on the role of these proteins across lower and higher eukaryotes and point to differences indicating evolutionary different pathways to shape mitotic chromosomes. Moreover, we discuss a controversial phenomenon of the mitotic chromosome ultrastructure – chromosome cavities – and using our super-resolution microscopy data, we contribute to its elucidation.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10608 - Biochemistry and molecular biology

Result continuities

  • Project

    <a href="/en/project/EF16_019%2F0000827" target="_blank" >EF16_019/0000827: Plants as a tool for sustainable global development</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2020

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Computational and Structural Biotechnology Journal

  • ISSN

    2001-0370

  • e-ISSN

  • Volume of the periodical

    18

  • Issue of the periodical within the volume

    FEB 3

  • Country of publishing house

    SE - SWEDEN

  • Number of pages

    9

  • Pages from-to

    1311-1319

  • UT code for WoS article

    000607350300007

  • EID of the result in the Scopus database

    2-s2.0-85079371547