Mitotic chromosome organization: General rules meet species-specific variability
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F20%3A00531604" target="_blank" >RIV/61389030:_____/20:00531604 - isvavai.cz</a>
Result on the web
<a href="http://doi.org/10.1016/j.csbj.2020.01.006" target="_blank" >http://doi.org/10.1016/j.csbj.2020.01.006</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.csbj.2020.01.006" target="_blank" >10.1016/j.csbj.2020.01.006</a>
Alternative languages
Result language
angličtina
Original language name
Mitotic chromosome organization: General rules meet species-specific variability
Original language description
Research on the formation of mitotic chromosomes from interphase chromatin domains, ongoing for several decades, made significant progress in recent years. It was stimulated by the development of advanced microscopic techniques and implementation of chromatin conformation capture methods that provide new insights into chromosome ultrastructure. This review aims to summarize and compare several models of chromatin fiber folding to form mitotic chromosomes and discusses them in the light of the novel findings. Functional genomics studies in several organisms confirmed condensins and cohesins as the major players in chromosome condensation. Here we compare available data on the role of these proteins across lower and higher eukaryotes and point to differences indicating evolutionary different pathways to shape mitotic chromosomes. Moreover, we discuss a controversial phenomenon of the mitotic chromosome ultrastructure – chromosome cavities – and using our super-resolution microscopy data, we contribute to its elucidation.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10608 - Biochemistry and molecular biology
Result continuities
Project
<a href="/en/project/EF16_019%2F0000827" target="_blank" >EF16_019/0000827: Plants as a tool for sustainable global development</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Computational and Structural Biotechnology Journal
ISSN
2001-0370
e-ISSN
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Volume of the periodical
18
Issue of the periodical within the volume
FEB 3
Country of publishing house
SE - SWEDEN
Number of pages
9
Pages from-to
1311-1319
UT code for WoS article
000607350300007
EID of the result in the Scopus database
2-s2.0-85079371547