Phytochemicals and antimicrobial properties of Thai edible plant extracts and their prebiotic-like effects

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F24%3A00600246" target="_blank" >RIV/61389030:_____/24:00600246 - isvavai.cz</a>

Alternative codes found

RIV/61989592:15310/24:73628626

Result on the web

<a href="https://doi.org/10.1016/j.jafr.2024.101152" target="_blank" >https://doi.org/10.1016/j.jafr.2024.101152</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jafr.2024.101152" target="_blank" >10.1016/j.jafr.2024.101152</a>

Result language

angličtina

Original language name

Phytochemicals and antimicrobial properties of Thai edible plant extracts and their prebiotic-like effects

Original language description

In this study, the phytochemicals and antimicrobial activities of ethanolic extracts of Thai edible plants, green tea, red cotton tree flower, fingerroot and ginger were evaluated. The plant extracts were taken for evaluation of antimicrobial activities against Cutibacterium acnes DMST 14916, Staphylococcus epidermidis TISTR 518, and Staphylococcus aureus TISTR 746. The minimum inhibitory concentrations (MICs) of green tea, fingerroot, and ginger extracts against C. acnes DMST 14916 were 3.92, 0.49, and 7.85 mg cm-3, respectively and the minimum bacteriostatic concentrations (MBCs) were 3.92, 0.49, and 7.85 mg cm-3, respectively. The MICs and MBCs of fingerroot extract against S. epidermidis TISTR 518 were 0.12 and 0.49 mg cm-3, respectively, while those against S. aureus TISTR 746 were 0.12 and 0.98 mg cm-3, respectively. Red cotton tree flower extract showed no antimicrobial activity against the acne-causing bacteria. By scanning electron microscopy (SEM) evaluation, the bacterial cells treated with the plant extracts revealed visible shrinkages compared to the smooth cell surfaces of the controls. The phytochemicals in the plant extracts were analysed by liquid chromatography with tandem mass spectrometry (LC-MS/MS). Well-known antimicrobial compounds like azelaic acid, embelin and kaempferol 3-rutinoside-4 '-glucoside were identified in all extracts. The cytotoxic effects of the plant extracts on human cell lines were further investigated. The green tea extract was slightly toxic to HaCaT cells found at the initial concentration of 62.5 mg cm-3, but not toxic to MRC-5 cells. The fingerroot and ginger extracts had no cytotoxicity on HaCaT cells, but promoted the MRC-5 cell proliferation. The combination effects of the plant extracts were prebiotic-like and indifferent effects. Regarding all results, the ethanolic extracts of green tea, fingerroot, and ginger could be used individually as natural anti-acne ingredients capable of further product development to improve human skin health.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

40401 - Agricultural biotechnology and food biotechnology

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Agriculture and Food Research

ISSN

2666-1543

e-ISSN

2666-1543

Volume of the periodical

16

Issue of the periodical within the volume

June

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

11

Pages from-to

101152

UT code for WoS article

001234511200001

EID of the result in the Scopus database

2-s2.0-85190111764