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Latest Developments of the Julia-Kocienski Olefination Reaction: Mechanistic Considerations

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F24%3A00600477" target="_blank" >RIV/61389030:_____/24:00600477 - isvavai.cz</a>

  • Alternative codes found

    RIV/61989592:15310/24:73627766

  • Result on the web

    <a href="https://doi.org/10.3390/molecules29122719" target="_blank" >https://doi.org/10.3390/molecules29122719</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.3390/molecules29122719" target="_blank" >10.3390/molecules29122719</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Latest Developments of the Julia-Kocienski Olefination Reaction: Mechanistic Considerations

  • Original language description

    Since its discovery, the Julia-Kocienski olefination reaction has over past 30 years become one of the key C-C connective methods that is used in late-stage natural product synthesis. The reaction proceeds under mild reaction conditions, with a wide substrate scope and functional group tolerance range and with high (E) selectivity. In this focused review, we discuss the reaction from a mechanistic point of view and disclose key features that play an important role in reaction selectivity. Finally, the mechanistic aspects of the newly developed modification of the Julia-Kocienski reaction, which allows the formation of both (E) and (Z) olefins from the same reaction partners, are discussed.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10401 - Organic chemistry

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2024

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Molecules

  • ISSN

    1420-3049

  • e-ISSN

    1420-3049

  • Volume of the periodical

    29

  • Issue of the periodical within the volume

    12

  • Country of publishing house

    CH - SWITZERLAND

  • Number of pages

    19

  • Pages from-to

    2719

  • UT code for WoS article

    001255992700001

  • EID of the result in the Scopus database

    2-s2.0-85197139473