GIBBERELLIN 3-OXIDASE genes regulate height and grain size in bread wheat
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F25%3A00639010" target="_blank" >RIV/61389030:_____/25:00639010 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1093/jxb/eraf151" target="_blank" >https://doi.org/10.1093/jxb/eraf151</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1093/jxb/eraf151" target="_blank" >10.1093/jxb/eraf151</a>
Alternative languages
Result language
angličtina
Original language name
GIBBERELLIN 3-OXIDASE genes regulate height and grain size in bread wheat
Original language description
Plant gibberellin (GA) concentrations are tightly regulated to optimize growth and development. GA 3-oxidases (GA3OX) catalyse a key GA biosynthesis step, converting precursor GAs into bioactive forms. We characterized seven GA3OX homologues in bread wheat (Triticum aestivum L.): a homoeologous triad of GA3OX2 genes expressed in vegetative and reproductive tissues, and four others (a homoeologous triad of GA3OX3 genes plus GA1OX1-B1) expressed predominantly in grains. ga3ox2 mutants are severely dwarfed and infertile due to very low bioactive GA concentrations, indicating that GA3OX2 is essential for normal wheat development. By contrast, ga3ox3 mutants have lower bioactive GA concentrations in grains, reducing grain size and weight, whereas ga1ox1 mutants accumulate high concentrations of bioactive GAs, producing larger grains. Unexpectedly, ga3ox3 and ga1ox1 alleles also affected height, possibly reflecting GA transport to vegetative tissues. Natural variation in adjacent GA3OX3-B1 and GA1OX1-B1 genes was associated with differences in grain size and weight, suggesting that a haplotype associated with larger grains was selected during modern breeding. Our study shows that the wheat GA3OX family has diversified roles, with GA3OX2 required for general growth and GA3OX3/GA1OX1 modulating GA concentrations during grain development. These findings highlight opportunities to exploit variation in GA biosynthetic pathways for wheat improvement.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10603 - Genetics and heredity (medical genetics to be 3)
Result continuities
Project
<a href="/en/project/EH22_008%2F0004581" target="_blank" >EH22_008/0004581: TowArds Next GENeration Crops (TANGENC)</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Experimental Botany
ISSN
0022-0957
e-ISSN
1460-2431
Volume of the periodical
76
Issue of the periodical within the volume
12
Country of publishing house
US - UNITED STATES
Number of pages
14
Pages from-to
3345-3358
UT code for WoS article
001485336400001
EID of the result in the Scopus database
2-s2.0-105013837951