All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”

Significant discrepancy in cyclosporin A post-dose concentrations when analyzed with specific RIA and HPLC method

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F10%3AA1000XT4" target="_blank" >RIV/61988987:17110/10:A1000XT4 - isvavai.cz</a>

  • Alternative codes found

    RIV/61989592:15110/10:10214981

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Significant discrepancy in cyclosporin A post-dose concentrations when analyzed with specific RIA and HPLC method

  • Original language description

    C-2 or AUC sparse sampling methods are widely recommended for therapeutic monitoring of cyclosporin A (CsA). One additional reason for promoting the C-2 sampling time in place of commonly used C-0 is that the C-2 level may actually provide more accuratemeasurement of parent drug concentration by immunoassays, as lower portion of metabolites has been formed 2 hours post-dose than at the steady-state trough time point. HPLC and RIA whole blood levels of CsA and its main metabolites AM1, AM9 and AWN werecompared during 12 hours profile after chronic administration.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FR - Pharmacology and apothecary chemistry

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Others

  • Publication year

    2010

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    INT J CLIN PHARM TH

  • ISSN

    0946-1965

  • e-ISSN

  • Volume of the periodical

    48

  • Issue of the periodical within the volume

    2

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    6

  • Pages from-to

  • UT code for WoS article

    000274770100001

  • EID of the result in the Scopus database