Changes of basal ganglia detected by transcrania sonography and 123I FP-CIT SPECT

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F10%3AA12011XC" target="_blank" >RIV/61988987:17110/10:A12011XC - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Changes of basal ganglia detected by transcrania sonography and 123I FP-CIT SPECT

Original language description

Diagnosis of Parkinson's disease (PD) could be difficult in early stages of the disease. Transcranial sonography (TCS) is able to detect structural changes in substantia nigra in PD patients. FP-CIT SPECT imaging could detect presynaptic dysfunction in several neurodegenerative disease. Methods: We examined 25 patients (19 male, mean age 57.2?8.4 years) during 2 years - 4 patients with ET, 12 PD patients, 7 PS patients, and 2 PMD patients. SN echogenicity and SN area were detected using TCS and SPECT evaluation of basal ganglia were performed using SPECT with DAT-ligand (123I-ioflupan) within 2 months after clinical examination. The sensitivity, specificity, positive predictive (PPV) and negative predictive (NPV) values for TCS and SPECT were evaluated.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FP - Other medical fields

OECD FORD branch

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Project

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Continuities

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

MOVEMENT DISORD

ISSN

0885-3185

e-ISSN

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Volume of the periodical

2

Issue of the periodical within the volume

25

Country of publishing house

US - UNITED STATES

Number of pages

1

Pages from-to

575-575

UT code for WoS article

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EID of the result in the Scopus database

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