TRANSCRANIAL SONOGRAPHY AND 123I-FP-CIT SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY IN MOVEMENT DISORDERS

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F27661989%3A_____%2F14%3AN0000010" target="_blank" >RIV/27661989:_____/14:N0000010 - isvavai.cz</a>

Alternative codes found

RIV/61989592:15110/14:33150662 RIV/00843989:_____/14:E0104146

Result on the web

<a href="https://www.umbjournal.org/article/S0301-5629(14)00299-3/abstract" target="_blank" >https://www.umbjournal.org/article/S0301-5629(14)00299-3/abstract</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ultrasmedbio.2014.05.014" target="_blank" >10.1016/j.ultrasmedbio.2014.05.014</a>

Result language

angličtina

Original language name

TRANSCRANIAL SONOGRAPHY AND 123I-FP-CIT SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY IN MOVEMENT DISORDERS

Original language description

Diagnosis of Parkinson's disease (PD) can be difficult in the early stages of the disease. The aim of the study described here was to assess the correlation between transcranial sonography (TCS) and I-123-FP-CIT ([I-123]ioflupane, N-omega-fluoropropyl-2 beta-carbomethoxy-3 beta-(4-[I-123]iodophenyl)nortropane) SPECT (single photon emission computed tomography) findings and the diagnosis of PD. A total of 49 patients were enrolled in the study: 29 patients with PD, 7 patients with other parkinsonian syndromes, 11 patients with essential tremor and 2 with psychogenic movement disorder. Substantia nigra echogenicity was measured using TCS. SPECT was performed using DaTSCAN ([I-123] ioflupane). TCS and SPECT findings were correlated in 84% of patients, with k = 0.62 (95% confidence interval: 0.38-0.86). TCS-measured substantia nigra echogenicity and SPECT-measured striatal binding ratio were negatively correlated (r = -0.326, p = 0.003). TCS/SPECT sensitivity, specificity and positive and negative predictive values for the diagnosis of PD were 89.7%/96.6%, 60.0%/70.0%, 76.5%/82.4% and 80.0%/93.3%, respectively. Both positive TCS and SPECT findings correlated significantly with the diagnosis of PD (k = 0.52, 95% confidence interval: 0.27-0.76, and k = 0.69, 95% confidence interval: 0.49-0.90, respectively). (C) 2014 World Federation for Ultrasound in Medicine & Biology.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30224 - Radiology, nuclear medicine and medical imaging

Project

—

Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Ultrasound in Medicine & Biology

ISSN

0301-5629

e-ISSN

1879-291X

Volume of the periodical

40

Issue of the periodical within the volume

10

Country of publishing house

US - UNITED STATES

Number of pages

7

Pages from-to

2365-2371

UT code for WoS article

000343144400006

EID of the result in the Scopus database

2-s2.0-84926211220