Serum levels of valproic acid during delivery in mothers and in umbilical cord-correlation with birth length and weight
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F15%3AA1601FK4" target="_blank" >RIV/61988987:17110/15:A1601FK4 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Serum levels of valproic acid during delivery in mothers and in umbilical cord-correlation with birth length and weight
Original language description
Maternal and umbilical cord serum levels were analyzed at delivery in a cohort of 58 women, between the years 1991-2013. The request forms for routine therapeutic drug monitoring were used as the data source. Maternal levels and dosing information were used for estimating the maternal apparent oral clearance and the paired umbilical cord and maternal levels for estimation of umbilical cord/maternal level ratios. Result. The levels varied from 5,3-59,5 mg/L in maternal and 5,4-72,1 mg/L in umbilical cordserum. The umbilical cord/maternal level ratios ranged from 0,64-2,49. Significant correlation was found between maternal and umbilical cord levels. Significant inverse correlations were found between birth length, and both maternal and umbilical cord levels in monotherapy.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FR - Pharmacology and apothecary chemistry
OECD FORD branch
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Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Biomed Pap Med Univ Palacky Olomouc
ISSN
1213-8118
e-ISSN
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Volume of the periodical
159
Issue of the periodical within the volume
4
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
6
Pages from-to
569-575
UT code for WoS article
000366566700009
EID of the result in the Scopus database
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