Altered expression pattern of SLAM family receptors on pathological B cells of patients with chronic lymphocytic leukemia
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F17%3AA1801TQV" target="_blank" >RIV/61988987:17110/17:A1801TQV - isvavai.cz</a>
Alternative codes found
RIV/00843989:_____/17:E0106348
Result on the web
<a href="http://dx.doi.org/10.1080/10428194.2016.1251593" target="_blank" >http://dx.doi.org/10.1080/10428194.2016.1251593</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1080/10428194.2016.1251593" target="_blank" >10.1080/10428194.2016.1251593</a>
Alternative languages
Result language
angličtina
Original language name
Altered expression pattern of SLAM family receptors on pathological B cells of patients with chronic lymphocytic leukemia
Original language description
Chronic lymphocytic leukemia (CLL) is a neoplastic diorder characterized by the clonal expansion of malignant B cells which accumulate in the bone marrow and peripheral blood. CLL B cells are strongly dependent on external signals from the microenvironment. Unless proliferation and survival signals are obtained, CLL cells usually undergo spontaneous apoptosis. Adhesion molecules are critical for the homing and retention of CLL cells in tissue compartments such as the bone marrow and secondary lymphatic tissues where microenvironment siutable to provide survival signals is present. Moreover, growth and survival signals provided to the CLL cells are largery contact-dependent.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30205 - Hematology
Result continuities
Project
—
Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Leukemia and Lymphoma
ISSN
1042-8194
e-ISSN
1029-2403
Volume of the periodical
58
Issue of the periodical within the volume
7
Country of publishing house
GB - UNITED KINGDOM
Number of pages
4
Pages from-to
1726-1729
UT code for WoS article
000399474000027
EID of the result in the Scopus database
2-s2.0-84996555344