Thrombolytic therapy with intravenous rt-PA in mild acute stroke patients: Analysis of sits registry data

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F17%3AA20020UM" target="_blank" >RIV/61988987:17110/17:A20020UM - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.jns.2017.08.1782" target="_blank" >http://dx.doi.org/10.1016/j.jns.2017.08.1782</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.jns.2017.08.1782" target="_blank" >10.1016/j.jns.2017.08.1782</a>

Result language
angličtina
Original language name
Thrombolytic therapy with intravenous rt-PA in mild acute stroke patients: Analysis of sits registry data
Original language description
Mild ischemic stroke severity is the most common reason for exclusion from thrombolytic treatment at the time of emergency department evaluation because of worry of a poor outcome and a potential risk of intracerebral hemorrhage. Previous studies suggest that up to 43% of ischemic stroke patients are not treated with intravenous recombinant tissue plasminogen activator (rt-PA) because of mild or rapidly improving symptoms. Also, the use of rt-PA is not recommended in current medical license and guidelines for these ischemic stroke patients because of an uncertain risk-benefit ratio. In contrast, recent studies demonstrate that up to one third of these patients dies or are permanently disabled. study objective was to evaluate safety and effectiveness of intravenous thrombolysis (IVT) in mild ischemic stroke patients with National Institutes of Health Stroke Scale score (NIHSS) less than 5
Czech name
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Czech description
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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