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Intravenous thrombolysis in acute ischemic stroke: standard and potential future applications

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F14%3A00078729" target="_blank" >RIV/00216224:14110/14:00078729 - isvavai.cz</a>

  • Alternative codes found

    RIV/00159816:_____/14:00061101

  • Result on the web

    <a href="http://dx.doi.org/10.1586/14737175.2014.934676" target="_blank" >http://dx.doi.org/10.1586/14737175.2014.934676</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1586/14737175.2014.934676" target="_blank" >10.1586/14737175.2014.934676</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Intravenous thrombolysis in acute ischemic stroke: standard and potential future applications

  • Original language description

    Acute ischemic stroke is a medical emergency requiring urgent treatment. Randomized clinical trial and Phase IV data have provided unequivocal evidence that intravenous thrombolysis with recombinant tissue plasminogen activator (rt-PA) improves early functional outcomes by restoring brain perfusion. Moreover, these studies have shed substantial light on the factors which are associated with more favorable outcome with tPA and are related to the highest benefit-to-risk ratio. Stroke physicians should consider vascular imaging techniques to aid decision making with thrombolytic therapy. The presence of intracranial occlusion is the target of treatment with early recanalization being the goal. Successful use of intravenous thrombolysis depends on a soundunderstanding of the decision-making process and organization of the treating team who strives for early treatment initiation and strict adherence to the protocol. Intravenous rt-PA within 4.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FH - Neurology, neuro-surgery, nuero-sciences

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/ED1.100%2F02%2F0123" target="_blank" >ED1.100/02/0123: St. Anne´s University Hospital Brno - International Clinical Research Center (FNUSA-ICRC)</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Expert Review of Neurotherapeutics

  • ISSN

    1473-7175

  • e-ISSN

  • Volume of the periodical

    14

  • Issue of the periodical within the volume

    8

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    14

  • Pages from-to

    879-892

  • UT code for WoS article

    000340482500004

  • EID of the result in the Scopus database