Single-agent venetoclax induces MRD-negative response in relapsed primary plasma cell leukemia with t(11;14)
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F19%3AA20021Q9" target="_blank" >RIV/61988987:17110/19:A20021Q9 - isvavai.cz</a>
Alternative codes found
RIV/00843989:_____/19:E0107410
Result on the web
<a href="https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ajh.25331" target="_blank" >https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ajh.25331</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/ajh.25331" target="_blank" >10.1002/ajh.25331</a>
Alternative languages
Result language
angličtina
Original language name
Single-agent venetoclax induces MRD-negative response in relapsed primary plasma cell leukemia with t(11;14)
Original language description
To the Editor: Plasma cell leukemia (PCL) is the most aggressive form of plasma cell dyscrasia. It is characterized by the presence of more than 20% and/or more than 2 × 109 /L of circulating plasma cells (PCs). Primary plasma cell leukemia (pPCL) that presents de novo should be distinguished from secondary PCL, which corresponds to the leukemic transformation of pre-existing multiple myeloma (MM). Primary PCL is characterized by an increased frequency of adverse laboratory and clinical features as well as higher genetic instability than MM. Despite the introduction of novel agents into clinical practice, the prognosis of pPCL remains poor, with an estimated overall survival of 1-2 years in elderly patients and about 3 years in younger patients eligible for stem cell transplantation (SCT).1,2
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30205 - Hematology
Result continuities
Project
—
Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
AMERICAN JOURNAL OF HEMATOLOGY
ISSN
0361-8609
e-ISSN
1096-8652
Volume of the periodical
94
Issue of the periodical within the volume
1
Country of publishing house
US - UNITED STATES
Number of pages
2
Pages from-to
'E35'-'E37'
UT code for WoS article
000453909800019
EID of the result in the Scopus database
2-s2.0-85057288241