The Effect of Botulinum Toxin Type A Injections on Stricture Formation, Leakage Rates, Esophageal Elongation, and Anastomotic Healing Following Primary Anastomosis in a Long- and Short-Gap Esophageal Atresia Model - A Protocol for a Randomized, Controlled, Blinded Trial in Pigs

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F21%3AA2202E9Q" target="_blank" >RIV/61988987:17110/21:A2202E9Q - isvavai.cz</a>
Alternative codes found
RIV/00843989:_____/21:E0109146
Result on the web
<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362621/pdf/ijsp-25-1-156.pdf" target="_blank" >https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362621/pdf/ijsp-25-1-156.pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.29337/ijsp.156" target="_blank" >10.29337/ijsp.156</a>

Result language
angličtina
Original language name
The Effect of Botulinum Toxin Type A Injections on Stricture Formation, Leakage Rates, Esophageal Elongation, and Anastomotic Healing Following Primary Anastomosis in a Long- and Short-Gap Esophageal Atresia Model - A Protocol for a Randomized, Controlled, Blinded Trial in Pigs
Original language description
Esophageal atresia (EA) is a congenital malformation affecting 1:3000- 4500 newborns. Approximately 15% have a long-gap EA (LGEA), in which case a primary anastomosis is often impossible to achieve. To create continuity of the esophagus patients instead have to undergo lengthening procedures or organ interpositions; methods associated with high morbidity and poor functional outcomes. Esophageal injections of Botulinum Toxin Type A (BTX-A) could enable primary anastomosis and mitigate stricture formation through decreased tissue tension.
Czech name
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Czech description
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Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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