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Diagnostics Accuracy of Magnetic Resonance Imaging in Detection of Atherosclerotic Plaque Characteristics in Carotid Arteries Compared to Histology: A Systematic Review

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F24%3AA250387C" target="_blank" >RIV/61988987:17110/24:A250387C - isvavai.cz</a>

  • Result on the web

    <a href="https://onlinelibrary.wiley.com/doi/10.1002/jmri.29522" target="_blank" >https://onlinelibrary.wiley.com/doi/10.1002/jmri.29522</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1002/jmri.29522" target="_blank" >10.1002/jmri.29522</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Diagnostics Accuracy of Magnetic Resonance Imaging in Detection of Atherosclerotic Plaque Characteristics in Carotid Arteries Compared to Histology: A Systematic Review

  • Original language description

    <jats:sec><jats:label/>Carotid plaque composition represents one of the main risk factors of future ischemic stroke. MRI provides excellent soft tissue contrast that can distinguish plaque characteristics. Our objective was to analyze the diagnostic accuracy of MRI imaging in the detection of carotid plaque characteristics compared to histology in patients with symptomatic and asymptomatic carotid atherosclerosis through a systematic review. After prospective registration in PROSPERO (ID CRD42022329690), Medline Ovid, <jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="http://embase.com">Embase.com</jats:ext-link>, Cochrane Library, and Web of Science Core were searched without any search limitation up to May 27, 2022 to identify eligible articles. Of the 8168 studies, 53 (37 × 1.5 T MRI, 17 × 3 T MRI) evaluated MRI accuracy in the detection of 13 specific carotid plaque characteristics in 169 comparisons. MRI demonstrated high diagnostic accuracy for detection of calcification (3 T MRI: mean sensitivity 92%/mean specificity 90%; 1.5 T MRI: mean sensitivity 81%/mean specificity 91%), fibrous cap (1.5 T: 89%/87%), unstable plaque (1.5 T: 89%/87%), intraplaque hemorrhage (1.5 T: 86%/88%), and lipid‐rich necrotic core (1.5 T: 89%/79%). MRI also proved to have a high level of tissue discrimination for the carotid plaque characteristics investigated, allowing potentially for a better risk assessment and follow‐up of patients who may benefit from more aggressive treatments. These results emphasize the role of MRI as the first‐line imaging modality for comprehensive assessment of carotid plaque morphology, particularly for unstable plaque.</jats:sec><jats:sec><jats:title>Evidence Level</jats:title>2</jats:sec><jats:sec><jats:title>Technical Efficacy</jats:title>Stage 2</jats:sec>

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30224 - Radiology, nuclear medicine and medical imaging

Result continuities

  • Project

  • Continuities

    V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Others

  • Publication year

    2024

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    J MAGN RESON IMAGING

  • ISSN

    1053-1807

  • e-ISSN

    1522-2586

  • Volume of the periodical

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    27

  • Pages from-to

    1067-1093

  • UT code for WoS article

    001268140900001

  • EID of the result in the Scopus database

    2-s2.0-85197805055