Catalase in Leishmaniinae: With me or against me?
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17310%2F17%3AA1801OCS" target="_blank" >RIV/61988987:17310/17:A1801OCS - isvavai.cz</a>
Alternative codes found
RIV/60077344:_____/17:00485316 RIV/60076658:12310/17:43895455
Result on the web
<a href="http://dx.doi.org/10.1016/j.meegid.2016.06.054" target="_blank" >http://dx.doi.org/10.1016/j.meegid.2016.06.054</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.meegid.2016.06.054" target="_blank" >10.1016/j.meegid.2016.06.054</a>
Alternative languages
Result language
angličtina
Original language name
Catalase in Leishmaniinae: With me or against me?
Original language description
The catalase gene is a virtually ubiquitous component of the eukaryotic genomes. It is also present in the monoxenous (i.e. parasitizing solely insects) trypanosomatids of the subfamily Leishmaniinae, which have acquired the enzyme by horizontal gene transfer from a bacterium. However, as shown here, the catalase gene was secondarily lost from the genomes of all Leishmania sequenced so far. Due to the potentially key regulatory role of hydrogen peroxide in the inter-stagial transformation of Leishmania spp., this loss seems to be a necessary prerequisite for the emergence of a complex life cycle of these important human pathogens. Hence, in this group of protists, the advantages of keeping catalase were uniquely outweighed by its disadvantages. (C) 2016 Elsevier B.V. All rights reserved.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10608 - Biochemistry and molecular biology
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
INFECTION GENETICS AND EVOLUTION
ISSN
1567-1348
e-ISSN
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Volume of the periodical
50
Issue of the periodical within the volume
Červen
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
7
Pages from-to
121-127
UT code for WoS article
000399514100018
EID of the result in the Scopus database
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