Complex analyses of inverted repeats in mitochondrial genomes revealed their importance and variability
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17310%2F18%3AA1901P6O" target="_blank" >RIV/61988987:17310/18:A1901P6O - isvavai.cz</a>
Alternative codes found
RIV/68081707:_____/18:00492380 RIV/62156489:43110/18:43912954
Result on the web
<a href="https://academic.oup.com/bioinformatics/article/34/7/1081/4604597" target="_blank" >https://academic.oup.com/bioinformatics/article/34/7/1081/4604597</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1093/bioinformatics/btx729" target="_blank" >10.1093/bioinformatics/btx729</a>
Alternative languages
Result language
angličtina
Original language name
Complex analyses of inverted repeats in mitochondrial genomes revealed their importance and variability
Original language description
MotivationThe NCBI database contains mitochondrial DNA (mtDNA) genomes from numerous species. We investigated the presence and locations of inverted repeat sequences (IRs) in these mtDNA sequences, which are known to be important for regulating nuclear genomes.ResultsIRs were identified in mtDNA in all species. IR lengths and frequencies correlate with evolutionary age and the greatest variability was detected in subgroups of plants and fungi and the lowest variability in mammals. IR presence is non-random and evolutionary favoured. The frequency of IRs generally decreased with IR length, but not for IRs 24 or 30?bp long, which are 1.5 times more abundant. IRs are enriched in sequences from the replication origin, followed by D-loop, stem-loop and miscellaneous sequences, pointing to the importance of IRs in regulatory regions of mitochondrial DNA.Availability and ImplementationData were produced using Palindrome analyser, freely available on the web at http://bioinformatics.ibp.cz.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10600 - Biological sciences
Result continuities
Project
<a href="/en/project/GA15-21855S" target="_blank" >GA15-21855S: Influence of conformation motifs and epigenetic modifications to DNA binding properties of p53 family proteins</a><br>
Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
BIOINFORMATICS
ISSN
1367-4803
e-ISSN
1460-2059
Volume of the periodical
34
Issue of the periodical within the volume
7
Country of publishing house
GB - UNITED KINGDOM
Number of pages
5
Pages from-to
1081-1085
UT code for WoS article
000428840000001
EID of the result in the Scopus database
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