Molecular characterization of Leishmania RNA virus 2 in Leishmania major from Uzbekistan

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17310%2F19%3AA200229G" target="_blank" >RIV/61988987:17310/19:A200229G - isvavai.cz</a>
Alternative codes found
RIV/00216224:14740/19:00113264
Result on the web
<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826456/pdf/genes-10-00830.pdf" target="_blank" >https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826456/pdf/genes-10-00830.pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/genes10100830" target="_blank" >10.3390/genes10100830</a>

Result language
angličtina
Original language name
Molecular characterization of Leishmania RNA virus 2 in Leishmania major from Uzbekistan
Original language description
Here we report sequence and phylogenetic analysis of two new isolates of Leishmania RNA virus 2 (LRV2) found in Leishmania major isolated from human patients with cutaneous leishmaniasis in south Uzbekistan. These new virus-infected flagellates were isolated in the same region of Uzbekistan and the viral sequences differed by only nineteen SNPs, all except one being silent mutations. Therefore, we concluded that they belong to a single LRV2 species. New viruses are closely related to the LRV2-Lmj-ASKH documented in Turkmenistan in 1995, which is congruent with their shared host (L. major) and common geographical origin.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30310 - Parasitology

Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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