First report of putative Leishmania RNA virus 2 (LRV2) in Leishmania infantum strains from canine and human visceral leishmaniasis cases in the southeast of Brazil

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17310%2F23%3AA2402MYJ" target="_blank" >RIV/61988987:17310/23:A2402MYJ - isvavai.cz</a>

Result on the web

<a href="https://pubmed.ncbi.nlm.nih.gov/37729273/" target="_blank" >https://pubmed.ncbi.nlm.nih.gov/37729273/</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1590/0074-02760230071" target="_blank" >10.1590/0074-02760230071</a>

Result language

angličtina

Original language name

First report of putative Leishmania RNA virus 2 (LRV2) in Leishmania infantum strains from canine and human visceral leishmaniasis cases in the southeast of Brazil

Original language description

BACKGROUND Leishmania RNA virus 1 (LRV1) is commonly found in South American Leishmania parasites belonging to the subgenus Viannia, whereas Leishmania RNA virus 2 (LRV2) was previously thought to be restricted to the Old-World pathogens of the subgenus Leishmania. OBJECTIVES In this study, we investigated the presence of LRV2 in strains of Leishmania (L.) infantum, the causative agent of visceral leishmaniasis (VL), originating from different hosts, clinical forms, and geographical regions. METHODS A total of seventy-one isolates were screened for LRV2 using semi-nested reverse transcription-polymerase chain reaction (RT-PCR) targeting the RNA-dependent RNA polymerase (RdRp) gene. FINDINGS We detected LRV2 in two L. infantum isolates (CUR268 and HP-EMO) from canine and human cases, respectively. MAIN CONCLUSIONS To the best of our knowledge, this is the first detection of LRV2 in the New World.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10606 - Microbiology

Project

<a href="/en/project/GA20-22689S" target="_blank" >GA20-22689S: Leishmaniaviruses in trypanosomatids</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2023

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

MEMORIAS DO INSTITUTO OSWALDO CRUZ

ISSN

0074-0276

e-ISSN

1678-8060

Volume of the periodical

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Issue of the periodical within the volume

118

Country of publishing house

BR - BRAZIL

Number of pages

8

Pages from-to

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UT code for WoS article

001076419900001

EID of the result in the Scopus database

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