Common structural patterns in the maxicircle divergent region of Trypanosomatidae

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17310%2F20%3AA21025CX" target="_blank" >RIV/61988987:17310/20:A21025CX - isvavai.cz</a>
Result on the web
<a href="https://www.mdpi.com/2076-0817/9/2/100/htm" target="_blank" >https://www.mdpi.com/2076-0817/9/2/100/htm</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/pathogens9020100" target="_blank" >10.3390/pathogens9020100</a>

Result language
angličtina
Original language name
Common structural patterns in the maxicircle divergent region of Trypanosomatidae
Original language description
Maxicircles of all kinetoplastid flagellates are functional analogs of mitochondrial genome of other eukaryotes. They consist of two distinct parts, called the coding region and the divergent region (DR). The DR is composed of highly repetitive sequences and, as such, remains the least explored segment of a trypanosomatid genome. It is extremely difficult to sequence and assemble, that is why very few full length maxicircle sequences were available until now. Using PacBio data, we assembled 17 complete maxicircles from different species of trypanosomatids. Here we present their large-scale comparative analysis and describe common patterns of DR organization in trypanosomatids.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30109 - Pathology

Project
<a href="/en/project/EF16_019%2F0000759" target="_blank" >EF16_019/0000759: Centre for research of pathogenicity and virulence of parasites</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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