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Beta-lactam resistance development during the treatment processes of municipal wastewater treatment plants

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17310%2F21%3AA2202ABN" target="_blank" >RIV/61988987:17310/21:A2202ABN - isvavai.cz</a>

  • Alternative codes found

    RIV/61388971:_____/21:00547706 RIV/61989100:27710/21:10247560 RIV/00064165:_____/21:10430470 RIV/00216208:11310/21:10430470

  • Result on the web

    <a href="https://www.sciencedirect.com/science/article/pii/S0045653521012200" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0045653521012200</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.chemosphere.2021.130749" target="_blank" >10.1016/j.chemosphere.2021.130749</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Beta-lactam resistance development during the treatment processes of municipal wastewater treatment plants

  • Original language description

    This work monitored the effect of a municipal and a village wastewater treatment plant (WWTP) technology on the fate of beta-lactam resistance genes in bacterial populations in different phases of the wastewater treatment process. In case of the municipal WWTP1, the bacteria possessing a high ampicillin resistance (minimal inhibitory concentration (MIC) values of 20 mg/mL) accumulated in the sedimentation tank, which was accompanied with a higher concentration of ampicillin in the wastewater samples (28.09 ng/L) and an increase in the relative abundance of the blaTEM gene in the bacterial population. However, an opposite trend was revealed with the blaNDM-1 gene, making the sedimentation processes of WWTP1 crucial only for the accumulation of the blaTEM gene. Similarly, the comparison with the WWTP2 showed that the accumulation of the ampicillin resistance in bacterial population probably depended on the WWTP technology and wastewater composition. Out of the four tested resistance genes (blaTEM, blaKPC, blaNDM-1, and blaOXA-48), blaTEM and blaNDM-1 genes were the only two detected in this study. According to NGS analysis of bacterial 16 S rRNA gene, Gammaproteobacteria dominated the ampicillin-resistant bacteria of the WWTP sedimentation tanks. Their relative abundance in the bacterial population also increased during the sedimentation processes in WWTP1. It could indicate the role of the bacterial taxon in ampicillin resistance accumulation in this WWTP and show that only 9.29% of the original bacterial population from the nitrification tank is involved in the documented shifts in beta-lactam resistance of the bacterial population.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10606 - Microbiology

Result continuities

  • Project

    <a href="/en/project/EF16_019%2F0000853" target="_blank" >EF16_019/0000853: Institute of Environmental Technology - Excellent Research</a><br>

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    CHEMOSPHERE

  • ISSN

    0045-6535

  • e-ISSN

    1879-1298

  • Volume of the periodical

    280

  • Issue of the periodical within the volume

    October 2021

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    8

  • Pages from-to

    130749

  • UT code for WoS article

    000662920300136

  • EID of the result in the Scopus database

    2-s2.0-85105262666