Differences in mitochondrial NADH dehydrogenase activities in trypanosomatids

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17310%2F21%3AA2202AEA" target="_blank" >RIV/61988987:17310/21:A2202AEA - isvavai.cz</a>
Result on the web
<a href="https://www.cambridge.org/core/journals/parasitology/article/differences-in-mitochondrial-nadh-dehydrogenase-activities-in-trypanosomatids/EA6B4A40B83A41E60C5D99B7E45AC446" target="_blank" >https://www.cambridge.org/core/journals/parasitology/article/differences-in-mitochondrial-nadh-dehydrogenase-activities-in-trypanosomatids/EA6B4A40B83A41E60C5D99B7E45AC446</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1017/S0031182020002425" target="_blank" >10.1017/S0031182020002425</a>

Result language
angličtina
Original language name
Differences in mitochondrial NADH dehydrogenase activities in trypanosomatids
Original language description
Complex I (NADH dehydrogenase) is the first enzyme in the respiratory chain. It catalyses the electron transfer from NADH to ubiquinone that is associated with proton pumping out of the matrix. In this study, we characterized NADH dehydrogenase activity in seven monoxenous trypanosomatid species: Blechomonas ayalai, Herpetomonas tarakana, Kentomonas sorsogonicus, Leptomonas seymouri, Novymonas esmeraldas, Sergeia podlipaevi and Wallacemonas raviniae. We also investigated the subunit composition of the complex I in dixenous Phytomonas serpens, in which its presence and activity have been previously documented. In addition to P. serpens, the complex I is functionally active in N. esmeraldas and S. podlipaevi. We also identified 24-32 subunits of the complex I in individual species by using mass spectrometry. Among them, for the first time, we recognized several proteins of the mitochondrial DNA origin.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10608 - Biochemistry and molecular biology

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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