Comparative Analysis of Three Trypanosomatid Catalases of Different Origin

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17310%2F22%3AA2302GKW" target="_blank" >RIV/61988987:17310/22:A2302GKW - isvavai.cz</a>
Result on the web
<a href="https://www.mdpi.com/2076-3921/11/1/46" target="_blank" >https://www.mdpi.com/2076-3921/11/1/46</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/antiox11010046" target="_blank" >10.3390/antiox11010046</a>

Result language
angličtina
Original language name
Comparative Analysis of Three Trypanosomatid Catalases of Different Origin
Original language description
Most trypanosomatid flagellates do not have catalase. In the evolution of this group, the gene encoding catalase has been independently acquired at least three times from three different bacterial groups. Here, we demonstrate that the catalase of Vickermania was obtained by horizontal gene transfer from Gammaproteobacteria, extending the list of known bacterial sources of this gene. Comparative biochemical analyses revealed that the enzymes of V. ingenoplastis, Leptomonas pyrrhocoris, and Blastocrithidia sp., representing the three independent catalase-bearing trypanosomatid lineages, have similar properties, except for the unique cyanide resistance in the catalase of the latter species.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10608 - Biochemistry and molecular biology

Project
<a href="/en/project/EF16_019%2F0000759" target="_blank" >EF16_019/0000759: Centre for research of pathogenicity and virulence of parasites</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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