An evolutionary perspective on Arf family GTPases

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17310%2F23%3AA2402N60" target="_blank" >RIV/61988987:17310/23:A2402N60 - isvavai.cz</a>
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S0955067423001175?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0955067423001175?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.ceb.2023.102268" target="_blank" >10.1016/j.ceb.2023.102268</a>

Result language
angličtina
Original language name
An evolutionary perspective on Arf family GTPases
Original language description
The Arf family GTPases are regulators of eukaryotic cellular organization, functioning in the secretory and endocytic pathways, in cilia and flagella, in cytoskeleton dynamics, and in lipid metabolism. We describe the evolution of this protein family and its well-studied regulators. The last eukaryotic common ancestor had fifteen members, and the current complement of Arf GTPases has been sculpted by gene loss and gene duplications since that point. Some Arf family GTPases (such as those that recruit vesicle coats in the secretory pathway) are present in virtually all eukaryotes, whereas others (such as those functioning in cilia/flagella) have a more limited distribution. A challenge for the future is understanding the full spectrum of Arf family functions throughout eukaryotes.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10601 - Cell biology

Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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