From drug delivery to environmental impact: Long-term behaviour of functionalized SBA-15 over a 20-year simulation
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17310%2F25%3AA2603C0I" target="_blank" >RIV/61988987:17310/25:A2603C0I - isvavai.cz</a>
Result on the web
<a href="https://linkinghub.elsevier.com/retrieve/pii/S2213343725042575" target="_blank" >https://linkinghub.elsevier.com/retrieve/pii/S2213343725042575</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.jece.2025.119561" target="_blank" >10.1016/j.jece.2025.119561</a>
Alternative languages
Result language
angličtina
Original language name
From drug delivery to environmental impact: Long-term behaviour of functionalized SBA-15 over a 20-year simulation
Original language description
The long-term environmental stability of mesoporous silica is a critical yet often overlooked factor in itsapplication as a drug delivery carrier. In this study, pristine and functionalized SBA-15 with polar (amine (–NH₂),thiol (–SH), polyethylenimine (–PEI)) and non-polar (methyl (–CH₃), phenyl (–Ph)) groups were subjected toaccelerated ageing in aqueous and soil environments simulating multi-year exposure. Pristine SBA-15 exhibitedsignificant but incomplete loss of porosity (SBET decreased from 729 to 514 m² g⁻¹). Hydrophilic modificationswere least stable: SBA-15-NH₂ lost > 60 % of SBET after aqueous exposure, while SBA-15-PEI showed an apparent~16 % increase in surface area due to partial polymer leaching. In contrast, non-polar groups enhanced resilience,with SBA-15-CH₃ retaining 82 % and SBA-15-Ph 76 % of initial SBET after aqueous ageing. Soil exposureinduced more complex deterioration via ion exchange, mineral deposition, and adsorption of organic matter,with polar groups most affected. Importantly, the silica matrix remained structurally intact, demonstratingintrinsic stability. These findings highlight that functionalization strongly dictates environmental fate, withhydrophobic groups ensuring higher resilience. The results provide guidance for designing sustainable mesoporoussilica carriers with reduced environmental risks and improved regulatory compliance.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10500 - Earth and related environmental sciences
Result continuities
Project
<a href="/en/project/LUASK22049" target="_blank" >LUASK22049: Monolithic, hierarchically porous MOF-carbon composites for environmental applications</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Environmental Chemical Engineering
ISSN
2213-2929
e-ISSN
2213-3437
Volume of the periodical
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Issue of the periodical within the volume
6
Country of publishing house
GB - UNITED KINGDOM
Number of pages
11
Pages from-to
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UT code for WoS article
001588566700001
EID of the result in the Scopus database
2-s2.0-105020984276