Radiation measurements using Timepix3 with silicon sensor and bare chip in proton beams for FLASH radiotherapy

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989100%3A27240%2F25%3A10257768" target="_blank" >RIV/61989100:27240/25:10257768 - isvavai.cz</a>

Result on the web

<a href="https://iopscience.iop.org/article/10.1088/1748-0221/20/04/C04030" target="_blank" >https://iopscience.iop.org/article/10.1088/1748-0221/20/04/C04030</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1088/1748-0221/20/04/C04030" target="_blank" >10.1088/1748-0221/20/04/C04030</a>

Result language

angličtina

Original language name

Radiation measurements using Timepix3 with silicon sensor and bare chip in proton beams for FLASH radiotherapy

Original language description

This study investigates the response of Timepix3 semiconductor pixel detectors in proton beams of varying intensities, with a focus on FLASH proton therapy. Using the Timepix3 application-specific integrated circuit (ASIC) chip, we measured the spatial and spectral characteristics of 220 MeV proton beams delivered in short pulses. The experimental setup involved Minipix readout electronics integrated with a Timepix3 chipboard in a flexible architecture, and an Advapix Timepix3 with a silicon sensor. Measurements were carried out with Timepix3 detectors equipped with experimental gallium arsenide (GaAs) and silicon (Si) sensors. We also investigated the response of a bare Timepix3 ASIC chip (without sensor). The detectors were placed within a waterproof holder attached to the positioning system of the IBA Blue water phantom, with additional measurements performed in air behind a 2 cm-thick polymethyl methacrylate (PMMA) phantom. The results demonstrated the capability of the Timepix3 detectors to measure time-over-threshold (ToT, deposited energy) and event counts (number of events in a pixel) in both conventional and ultra-high-dose-rates (UHDR) proton beams. The bare ASIC chip configuration sustained up to a dose rate (DR) of 270 Gy/s, the maximum tested intensity, although it exhibited limited spatial resolution due to low detection efficiency. contrast, Minipix Timepix3 with experimental GaAs sensors showed saturation at low DR similar to 5 Furthermore, the Advapix Timepix3 detector was used in both standard and customized configurations. In the standard configuration (Ikrum = 5), the detector showed saturation at DR similar to 5 Gy/s. But, in customized configuration when the per-pixel discharging signal (called &quot;Ikrum&quot;) was increased (Ikrum = 80), the detector demonstrated enhanced performance by reducing the duration of the ToT signal, allowing beam spot imaging up to DR=similar to 28 Gy/s in the plateau region of the Bragg curve. For DR or higher, the frame acquisition time was reduced to the order of microseconds, meaning only fraction of the pulse (with pulse lengths on the order of milliseconds) was captured.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10304 - Nuclear physics

Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2025

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Instrumentation

ISSN

1748-0221

e-ISSN

1748-0221

Volume of the periodical

20

Issue of the periodical within the volume

4

Country of publishing house

GB - UNITED KINGDOM

Number of pages

12

Pages from-to

"C04030(0)"-"C04030(11)"

UT code for WoS article

001472034600001

EID of the result in the Scopus database

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