Addition of platelet concentrate to Dermo-Epidermal Skin Graft in deep burn trauma reduces scarring and need for revision surgeries

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989100%3A27510%2F14%3A86091600" target="_blank" >RIV/61989100:27510/14:86091600 - isvavai.cz</a>

Alternative codes found

RIV/00843989:_____/14:E0104022

Result on the web

<a href="http://dx.doi.org/10.5507/bp.2013.070" target="_blank" >http://dx.doi.org/10.5507/bp.2013.070</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5507/bp.2013.070" target="_blank" >10.5507/bp.2013.070</a>

Result language

angličtina

Original language name

Addition of platelet concentrate to Dermo-Epidermal Skin Graft in deep burn trauma reduces scarring and need for revision surgeries

Original language description

Backround: Deep skin burn injuries, especially those on the face, hands, feet, genitalia and perineum represent significant therapeutic challenges. Autologous dermo-epidermal skin grafts (DESG) have become standard of care for treating deep burns. Additionally, human autologous thrombin activated autologous platelet concentrate (APC) has gained acceptance in the setting of wounds. While each of these interventions has been independently shown to accelerate healing, the combination of the two has never been evaluated. We hypothesized that the addition of platelets (source of growth factors and inhibitors necessary for tissue repair) to the DESG (source of progenitor cells and of tissue proteases necessary for spatial and temporal control of growth regulators released from platelets) would create the optimal environment for the reciprocal interaction of cells within the healing tissues. Methods: We used clinical examination (digital photography), standardised scales for evaluating pain a

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FI - Traumatology and orthopaedics

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Biomedical Papers of the the Faculty of Medicine of Palacký University, Olomouc Czech Republic

ISSN

1213-8118

e-ISSN

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Volume of the periodical

158

Issue of the periodical within the volume

2

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

17

Pages from-to

242-258

UT code for WoS article

000338628200014

EID of the result in the Scopus database

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