Preparation of antibacterial chlorhexidine/vermiculite and release study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989100%3A27640%2F17%3A10237001" target="_blank" >RIV/61989100:27640/17:10237001 - isvavai.cz</a>

Alternative codes found

RIV/61989100:27740/17:10237001 RIV/71009396:_____/17:N0000019

Result on the web

<a href="http://www.sciencedirect.com/science/article/pii/S0301751616302708" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0301751616302708</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.minpro.2016.12.002" target="_blank" >10.1016/j.minpro.2016.12.002</a>

Result language

angličtina

Original language name

Preparation of antibacterial chlorhexidine/vermiculite and release study

Original language description

The antibacterial chlorhexidine/vermiculite (CA/Ver) was successfully prepared through the intercalation process and the stability of CA on the vermiculite matrix and was investigated by stirring in aqueous solutions under the influence of different pH and temperature. The content of CA was determined by total organic carbon (TOC) analysis before and after stability tests. The structure of all samples was characterized by X-ray powder diffraction (XRD) and Fourier–transforminfrared spectroscopy (FTIR). The antibacterial activity of prepared CA/Ver samples was evaluated by finding a minimum inhibitory concentration (MIC) against Enterococcus faecalis, Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa. The content of chlorhexidine ranged from 209 to 231.6 mg of CA in 1 g of the whole sample after the intercalation process. After stability study, only a slight outflow of CA from the Ver matrix (5%) was noted. The antibacterial test confirmed that the outflow of CA was negligible. After 30min of exposition the MIC of organovermiculite samples before and after stability test were the same for Staphylococcus aureus and Escherichia coli with value 3.33 (%; w/v) and the MIC decreased to 0.014 (%; w/v) with longer time of exposition (120 h). A small difference was observed at Enterococcus faecalis where MIC was 10 (%; w/v) after 30 min of exposition for the sample after stability test in neutral pH. However, after 24 h of treatment the MIC value decreased to 0.014 (%; w/v). And finally, bacterial strain Pseudomonas aeruginosa showed a great resistance against antibacterial organovermiculite samples and MIC did not decreased under 10 (%; w/v) even after 5 days of exposition.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

20505 - Composites (including laminates, reinforced plastics, cermets, combined natural and synthetic fibre fabrics; filled composites)

Project

<a href="/en/project/GAP210%2F11%2F2215" target="_blank" >GAP210/11/2215: Study and evaluation of vermiculite structures modified in role of nanofillers and substrates</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

International Journal of Mineral Processing

ISSN

0301-7516

e-ISSN

—

Volume of the periodical

159

Issue of the periodical within the volume

8 December 2016

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

7

Pages from-to

1-6

UT code for WoS article

000393720300001

EID of the result in the Scopus database

2-s2.0-85007089921